Dr. Mikaela Stewart | Biochemistry | Women Researcher Award

Dr. Mikaela Stewart | Biochemistry | Women Researcher Award

Dr. Mikaela Stewart, Texas Christian University, United States

Dr. Mikaela D. Stewart is an Associate Professor at Texas Christian Universityโ€™s Department of Biology, specializing in biochemistry and biophysics ๐Ÿ”ฌ. Her research investigates the conservation of transcriptional regulation by BRCA1 and BARD1 in Caenorhabditis elegans ๐Ÿงฌ, focusing on protein interactions and cancer-related mechanisms. She has published extensively in high-impact journals and has contributed to advancing the understanding of E3 ubiquitin ligases and their role in cellular regulation ๐Ÿงช. Dr. Stewart is passionate about mentoring students and advancing molecular biology through her work at TCU ๐Ÿซ.

Professional Profile:

Scopus

Summary of Suitability for Women Researcher Awards

Dr. Mikaela D. Stewart is highly deserving of the Women Researcher Award, as her academic achievements, groundbreaking research in cancer biology, and commitment to mentoring and advancing the field of molecular biology demonstrate excellence. Her contributions to the scientific community, particularly in understanding the protein interactions that influence gene expression and cellular regulation, are invaluable. Dr. Stewart embodies the qualities that the Women Researcher Award seeks to honorโ€”innovation, leadership, and a dedication to both scientific progress and mentoring the next generation of researchers.

Education & Experience

  • ๐ŸŽ“ Postdoctoral Fellow in Biochemistry, University of Washington (2017)
    • Advisor: Prof. Rachel Klevit
  • ๐ŸŽ“ Ph.D. in Biochemistry/Biophysics, Texas A&M University (2013)
    • Advisor: Prof. Tatyana Igumenova
    • Thesis: “Determining the intrinsic properties of the C1B domain that influence PKC ligand specificity and sensitivity to reactive oxygen species.”
  • ๐ŸŽ“ B.S. in Biology, Chemistry Minor, University of Central Arkansas (2007)
    • Advisor: Prof. Lori Isom
    • Thesis: “Cations stabilize unstacked nucleic acids in DNA and RNA structures.”
    • Graduated Summa cum laude

Professional Development

Dr. Stewartโ€™s professional development centers on her pioneering research in biochemistry and her mentoring roles at TCU ๐ŸŒฑ. As an active researcher, she has led numerous high-impact studies on transcriptional regulation and cancer-related protein interactions ๐Ÿ”ฌ. Her research on BRCA1 and BARD1 in C. elegans bridges molecular biology with potential cancer therapies ๐Ÿงฌ. Dr. Stewartโ€™s leadership in guiding undergraduate and graduate students, as well as her numerous awards, reflects her dedication to advancing the field ๐ŸŒŸ. She actively contributes to scientific communities through publications and conferences ๐Ÿ’ก.

Research Focus

Dr. Mikaela D. Stewartโ€™s research focuses on biochemistry and molecular biology, specifically in the realm of transcriptional regulation by BRCA1 and BARD1 in Caenorhabditis elegans ๐Ÿงฌ. Her work explores the role of E3 ubiquitin ligases in cellular regulation and cancer mechanisms ๐Ÿงช. She is dedicated to understanding protein interactions that influence gene expression and contribute to disease, particularly in the context of breast cancer and other genetic disorders ๐Ÿ”ฌ. Her studies aim to unlock new therapeutic strategies by targeting specific protein functions and pathways involved in gene regulation and cellular stress responses ๐ŸŒฑ.

Awards & Honors

  • ๐Ÿ† Chrissy Baker โ€“ American Society Molecular Biology and Biochemistry travel grant recipient (2024)
  • ๐Ÿ… Chrissy Baker โ€“ Student Research Competition Winner, TCU Biology (2024)
  • ๐Ÿฅ‡ Chrissy Baker โ€“ Three-minute Thesis College of Science and Engineering Winner (2023)
  • ๐Ÿ† Thu Uyen Nguyen โ€“ Outstanding Undergraduate Presentation at Texas Genetic Society Meeting (2022)
  • ๐Ÿ… Russell Vahrenkamp โ€“ Protein Science Anniversary Award โ€“ Virtual Symposium (2021)
  • ๐Ÿ† Davis Martin โ€“ College of Science and Engineering representative Boller Award Competition (2021)
  • ๐Ÿฅˆ Christine Hurd โ€“ Three-minute Thesis College of Science and Engineering Runner-up (2019)
  • ๐ŸŒŸ Selected for UW School of Medicine Postdoc Seminar Series (2016)
  • ๐Ÿ† Runner-up in the Texas A&M Biochemistry/Biophysics student research competition (2010 & 2012)
  • โœˆ๏ธ Experimental Nuclear Magnetic Resonance Conference travel grant recipient (2010)
  • โœˆ๏ธ Biochemistry Graduate Association travel grant recipient (five times, 2008-2013)

Publication Top Notes:

  • Conservation of transcriptional regulation by BRCA1 and BARD1 in Caenorhabditis elegans ๐Ÿงฌ๐Ÿ
    ๐Ÿ“– Cited by: 2.
  • A Model for the Rapid Assessment of Solution Structures for 24-Atom Macrocycles: The Impact of ฮฒ-Branched Amino Acids on Conformation ๐Ÿ”ฌ๐Ÿงช
    ๐Ÿ“– Cited by: 4.
  • The BRCA1/BARD1 ubiquitin ligase and its substrates ๐Ÿ”ฌ๐Ÿ’ก
    ๐Ÿ“– Cited by: 32.
  • BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1 ๐Ÿงฌ๐Ÿ”‘
    ๐Ÿ“– Cited by: 54.
  • De novo mutation in RING1 with epigenetic effects on neurodevelopment ๐Ÿง ๐Ÿงฌ
    ๐Ÿ“– Cited by: 22.